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新产品编号:1422727

Chemical Name: 3(S)-[(2S,5S,11bR)-2-(Benzyloxycarbamoyl)-3-oxo-2,3,5,6,11,11b-hexahydro-1H-indolizino[8,7-b]indol-5-ylcarbamoyl]-4-phenylbutyric acid
项目整合开发状态: Biological Testing
项目研究机构: CSIC (Originator), Universidad de Navarra (Originator)
合成路线:The condensation of carboxylic acid derivative (I) with the chiral amino acid trimethylsilylethyl ester (II) by means of BOP and triethylamine gives the amide (III),which is hydrolyzed at the trimethylsilylethyl ester with TFA to afford the target compound.

合成路线:The condensation of carboxylic acid derivative (I) with the chiral amino acid trimethylsilylethyl ester (II) by means of BOP and triethylamine gives the amide (III),which is hydrolyzed at the trimethylsilylethyl ester with TFA to afford the target compound.
📌 参考资料/链接:
参考文献标题:Highly constrained dipeptoid analogues containing a type II' beta-turn mimic as novel and selective CCK-A receptor ligands
文献作者:de la Figuera,N.; Mart�?Mart韓ez,M.; Herranz,R.; Garc�?L髉ez,M.T.; Latorre,M.; Cenarruzabeitia,E.; del Rio,J.; Gonz醠ez-Mu駃z,R.
参考来源:Bioorg Med Chem Lett 1999,9(1),43