新产品编号:2507979
Chemical Name: 3-(2,3-Difluorophenyl)-4-(2-oxo-2,3-dihydrobenzothiazol-5-ylamino)-1H-pyrrole-2,5-dione
项目整合开发状态: Biological Testing
项目研究机构: GlaxoSmithKline (Originator)
合成路线:The condensation of 3-chloro-4-(2,3-difluorophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione (I) with 5-amino-2,3-dihydrobenzothiazol-2-one (II) by means of TEA in refluxing methanol gives the target secondary amine.
📌 参考资料/链接：
参考文献标题:Pyrrole-2,5-dione derivs.for the treatment of diabetes
文献作者:Smith,D.G.; Haigh,D.; Ward,R.W.; Slingsby,B.P.(GlaxoSmithKline plc)
参考来源:WO 0174771