新产品编号:2422551
Chemical Name: N-Butyl-2-(4-fluorophenyl)acetamide
项目整合开发状态: Biological Testing
项目研究机构: China Medical College (Originator), Chung Shan Medical University (Originator), Taichung Veterans General Hospital (Originator)
合成路线:4-Fluorophenylacetic acid (I) is chlorinated by means of SOCl2 in refluxing benzene.The resultant acid chloride (II) is then reacted with butylamine (III) to produce the target amide
📌 参考资料/链接：
参考文献标题:4-Fluoro-N-butylphenylacetamide: A synthetic phenylacetate derivative that upregulates Bcl-X-S,activates caspase cascade and induces apoptosis in human squamous lung cancer CH27 cells
文献作者:Chan,H.C.; Kuo,S.C.; Liu,S.C.; Liu,C.H.; Hsu,S.L.
参考来源:Cancer Lett 2002,186(2),211