新产品编号:2411477

Chemical Name: (Z)-2-[6-[1-(4-Aminophenyl)-1-(4-methylcarbazono)methyl]-1,3-benzodioxol-5-yl]acetic acid methyl ester; (Z)-1-(4-Aminophenyl)-1-[6-(methoxycarbonylmethyl)-1,3-benzodioxol-5-yl]methanone N-methylsemicarbazone
项目整合开发状态: Preclinical
项目研究机构: Universit?degli Studi di Catanzaro (Originator), Universit?degli Studi di Messina (Originator), Universit?degli Studi di Milano (Originator), Universit?degli Studi di Modena (Originator), Universit?degli Studi di Pavia (Originator)
合成路线:Condensation of benzodiazepinone (I) with methyl isocyanate provides the 3 (N-methylcarbamoyl) derivative (II).Reduction of the nitro group of (II) with concomitant diazepinone ring cleavage in the presence of SnCl2 in refluxing MeOH then furnishes the title compound.