新产品编号:2345033
Chemical Name: cis-3,4',5-Trimethoxystilbene
项目整合开发状态: Biological Testing
项目研究机构: Arizona State University (Originator), National Institutes of Health (Originator)
合成路线:4-Methoxybenzyl bromide (I) is condensed with triphenylphosphine in refluxing toluene to produce the phosphonium salt (II).Subsequent Wittig condensation of (II) with 3,5-dimethoxybenzaldehyde (III) gives rise to a mixture of the title Z-stilbene and its E-isomer (IV),which can be separated by means of flash chromatography.
📌 参考资料/链接:
参考文献标题:Antineoplastic agents.465.Structural modification of resveratrol: Sodium resverastatin phosphate
文献作者:Pettit,G.R.; Grealish,M.P.; Jung,M.K.; Hamel,E.; Pettit,R.K.; Chapuis,J.-C.; Schmidt,J.M.
参考来源:J Med Chem 2002,45(12),2534