新产品编号:2341869

Chemical Name: 7,8,10,11,20,21,23,24-Octahydrodinaphtho[2,3-e:2',3'-n][1,10,4,7,13,16]dioxatetrathiacyclooctadecin-5,13,18,26-tetrone
项目整合开发状态: Biological Testing
项目研究机构: Taipei Medical College (Originator)
合成路线:Condensation of 1,4-naphthoquinone (I) with bis(2-mercaptoethyl) ether (II) produces the bis-(dihydroxynaphthalene) adduct (III),which is spontaneously oxidized to the bis-napthoquinone derivative (IV).Then,cyclization of (IV) with further bis-mercapto ether (II) in DMF under a positive pressure of O2 leads to the target crown ether derivative.