新产品编号:2335541
Chemical Name: 2-(2-Methylquinolin-4-ylamino)-N-phenylacetamide
项目整合开发状态: Preclinical
项目研究机构: Indian Institute of Chemical Biology (Originator)
合成路线:Acylation of aniline (I) with chloroacetyl chloride (II) in cold CH2Cl2 provides 2-chloro-N-phenylacetamide (III).Then,condensation of (III) with 4-aminoquinaldine (IV) in the presence of NaH in an inert atmosphere furnishes the title compound
📌 参考资料/链接:
参考文献标题:Synthesis of a novel quinoline derivative,2-(2-methylquinolin-4-ylamino)-N-phenylacetamide- A potential antileishmanial agent
文献作者:Sahu,N.P.; Pal,C.; Mandal,N.B.; Banerjee,S.; Raha,M.; Kundu,A.P.; Basu,A.; Ghosh,M.; Roy,K.; Bandyopadhyay,S.
参考来源:Bioorg Med Chem 2002,10(6),1687