Zn(6mpa-ma)2SO4
Chemical Name: Bis(N,6-dimethylpyridine-2-carboxamide)zinc sulfate
项目整合开发状态: Preclinical
项目研究机构: Kyoto Pharmaceutical University (Originator), Osaka City University (Originator), Osaka Municipal Technical Res. Institute (Originator)
合成路线:6-Methylpicolinic acid (I) is esterified with MeOH and H2SO4,and the resultant methyl ester (II) is further reacted with methylamine to afford amide (III).The target zinc complex is then obtained by treatment of picolinamide (III) with an aqueous solution of ZnSO4.
📌 参考资料/链接:
参考文献标题:Potential insulinominetic agents of zinc(II) complexes with picolinamide derivatives: Preparations of complexes,in vitro and in vivo studies
文献作者:Ueda,E.; Yoshikawa,Y.; Ishino,Y.; Sakurai,H.; Kojima,Y.
参考来源:Chem Pharm Bull 2002,50(3),337