MKH-57

Chemical Name: 2-[3-Allyl-5-(3-methyl-2,3-dihydrobenzothiazol-2-ylidene)-4-oxothiazolidin-2-ylidenemethyl]-1-methylpyridinium 4-methylbenzenesulfonate
项目整合开发状态: Biological Testing
项目研究机构: Fuji Photo Film (Originator)
合成路线:Condensation of the benzothiazolium salt (I) with 3-allylrhodanine (II) in the presence of Et3N afforded the benzothiazolylidene rhodanine (III).S-Methylation of (III) was accomplished by treatment with methyl p-toluenesulfonate at 120 C,yielding (IV).This was finally condensed with 1,2-dimethylpyridinium tosylate (V) in the presence of Et3N to provide the title compound.