新产品编号:2267515
Chemical Name: Cyclopropanecarboxylic acid 2-chloro-3-oxo-1-cyclohexen-1-yl ester
项目整合开发状态: Biological Testing
项目研究机构: Tunghai University (Originator)
合成路线:The chlorination of cyclohexane-1,3-dione (I) with chloramine T in acetonitrile gives 2-chlorocyclohexane-1,3-dione (II),which is finally condensed with cyclopropanecarbonyl chloride (III) by means of potassium tert-butoxide in THF to yield the target cyclohexenyl ester.
📌 参考资料/链接：
参考文献标题:SAR studies of 3-cyclopropanecarbonyloxy-2-cyclohexen-1-one as inhibitors of 4-hydroxyphenylpyruvate dioxygenase
文献作者:Lin,Y.-L.; Wu,C.-S.; Lin,S.-W.; Huang,J.-L.; Sun,Y.-S.; Yang,D.-Y.
参考来源:Bioorg Med Chem 2002,10(3),685