新产品编号:2082421
Chemical Name: N-[1-(2'-Deoxyuridin-5-yl)-2-iodoethyl]cyanamide
项目整合开发状态: Biological Testing
项目研究机构: University of Alberta (Originator)
合成路线:The title 1-cyanamido-2 iodoethyl derivative was synthesized by reaction of 5-vinyl-2'-deoxyuridine (I) with N-iodosuccinimide in the presence of cyanamide in cold dimethoxyethane.
📌 参考资料/链接:
参考文献标题:Synthesis and antiviral activity of novel 5-(1-cyanamide-2-haloethyl) and 5-(1-hydroxy(or methoxy)-2-azidoethyl)analogues of uracil nucleosides
文献作者:Kumar,R.; Rai,D.; Sharma,S.K.; Saffran,H.A.; Blush,R.; Tyrrell,D.L.
参考来源:J Med Chem 2001,44(21),3531