新产品编号:1959025

Chemical Name: 2-Methoxy-5-(3,4,5-trimethoxyphenoxymethyl)phenol
项目整合开发状态: Biological Testing
项目研究机构: Paterson Institute Cancer Research (Originator), Univ. Science and Technology Manchester (Originator)
合成路线:Isovanillin (I) was protected as the allyl ether (III) by treatment with allyl bromide (II) and K2CO3.Aldehyde reduction of (III) with NaBH4 gave alcohol (IV),which was converted to chloride (V) using SOCl2.Condensation of chloride (V) with the sodium salt of 3,4,5-trimethoxyphenol (VI) produced the corresponding ether (VII).Finally,deprotection of the allyl group of (VII) was achieved by treatment with Wilkinson�?catalyst and DABCO.