新产品编号:1922639

Chemical Name: 2(S)-(2-Hydroxy-5-nitrobenzylamino)-N-isopentyl-3-phenylpropionamide; N2-(2-Hydroxy-5-nitrobenzyl)-N1-isopentyl-L-phenylalanylamide
项目整合开发状态: Biological Testing
项目研究机构: Millennium (Originator)
合成路线:Coupling of N-Boc-phenylalanine (I) with amine (II) by means of HBTU and DIEA provides amide (III),whose Boc group is removed by treatment with HCl in dioxane to afford amine hydrochloride (IV).Finally,the target compound is obtained by reductive amination between amine (IV) and aldehyde (V) in MeOH in the presence of NaCNBH3.