新产品编号:1875179

Chemical Name: 2-[(1R,3aR,7aR)-1-[1(R),5-Dimethylhexyl]-7a-methyloctahydro-4H-inden-4-ylidene]acetic acid
项目整合开发状态: Biological Testing
项目研究机构: Taiho (Originator)
合成路线:Indanone derivative (II) was obtained as the major product from the ozonolysis of vitamin D3 (I).Horner-Emmons condensation of ketone (II) with trimethyl phosphonoacetate (III) provided the unsaturated ester (IV).This was finally hydrolyzed to the corresponding carboxylic acid by treatment with LiOH.