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新产品编号:1862523

Chemical Name: 3-[13(R)-Acetoxy-13-[octahydro-5'(R)-[1(S)-acetoxy-5(S)-(2,3,4,6-O-tetrakis(acetyl)-beta-D-glucopyranosyloxy)undecyl][2(R),2'(R)-bifuran-5(R)-yl]tridecyl]-5(S)-methyl-2(5H)-furanone
项目整合开发状态: Biological Testing
项目研究机构: CNRS (Originator)
合成路线:Squamocin (I) was isolated from the seeds of Annona spinescens,the bark of Annona salzmanii,and the seeds of Annona atemoya,and was dried by azeotropic distillation with toluene.Glycosylation with pentaacetyl-alpha-D-glucopyranose (II) in the presence of boron trifluoride etherate produced a mixture of the target 15,24-diacetyl-28-(tetraacetyl-beta-D-glucosyl)squamocin and three other acetylated glucosides,which were separated by means of centrifugal partition chromatography.
📌 参考资料/链接:
参考文献标题:Synthesis,spectroscopy,and cytotoxicity of glycosylated acetogenin derivatives as promising molecules for cancer therapy
文献作者:Queiroz,E.F.; Roblot,F.; Duret,P.; Figad鑢e,B.; Gouyette,A.; Lapr関ote,O.; Serani,L.; Hocquemiller,R.
参考来源:J Med Chem 2000,43(8),1604