Org-2766
3-(甲基磺基基)-L-α-氨基丁酰-L-α-谷氨酰-L-组氨酰-3-苯基-L-丙氨酰-D-赖氨酰-L-丙氨酸Chemical Name: gamma-(Methylsulfonyl)-L-alpha-aminobutyryl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-D-lysyl-L-phenylalanine; H-Met(--O2)-Glu-His-Phe-D-Lys-Phe-OH; L-Methionyl-L-glutamyl-L-histidyl-L-phenyl-alanyl-D-lysyl-L-phenylalanine S,S-dioxide
CAS No. 50913-82-1
项目整合开发状态: Phase III
项目研究机构: Organon (Originator)
合成路线:A new synthesis of ORG-2766 has been performed using the normal methods of peptide synthesis and following the scheme presented.This method has been used to prepare ORG-2766 labeled with 11C at the methanesulfonyl group of the methionine analogue.
📌 参考资料/链接:
参考文献标题:Synthesis and 11C-labelling of the ACTH fragment analogue H-Met(O2)-Glu-His-Phe-D-Lys-Phe-OH (Org 2766) via its homocysteine-containing precursor
文献作者:Van Nispen,J.W.; Janssen,W.P.A.; Melgers,P.A.T.A.; Janssen,P.S.L.; Jansen,J.F.G.A.; Vaalburg,W.
参考来源:Int J Pept Protein Res 1990,36(2),167