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Ropitoin hydrochloride, TR-2985

2,4-吡唑烷二酮,5-(4-甲氧基苯基)-5-苯基-3-[3-(4-苯基-1-哌啶基)丙基]-盐酸盐(1:1) 罗匹妥英 Chemical Name: 5-(4-Methoxyphenyl)-5-phenyl-3-[3-(4-phenyl-1-piperidinyl)propyl]-2,4-imidazolidinedione hydrochloride; 5-(p-Methoxyphenyl)-5-phenyl-3-[3-(4-phenyl-1-piperidinyl)propyl]hydantoin hydrochloride
CAS No. 56079-80-2, 56079-81-3 (free base)
项目整合开发状态: Biological Testing
项目研究机构: Bayer (Originator)
合成路线:By condensation of 5-(4-methoxyphenyl)-5-phenylhydantoin (I) with 1-(3-chloropropyl)-4-phenylpiperidine (II) by means of sodium ethoxide in refluxing ethanol followed by a treatment with HCl.
📌 参考资料/链接:
参考文献标题:Ropitoin Hydrochloride
文献作者:Hillier,K.; Castar,J.
参考来源:Drugs Fut 1980,5(9),447

📄 详细内容


合成路线:By condensation of 5-(4-methoxyphenyl)-5-phenylhydantoin (I) with 1-(3-chloropropyl)-4-phenylpiperidine (II) by means of sodium ethoxide in refluxing ethanol followed by a treatment with HCl.
参考文献标题:
文献作者:Hayao,S.; et al.
参考来源:US 3892748


产品链接: CAS No. 56079-80-2››

产品链接: CAS No.56079-81-3››