Medosan-27, MED-27
1H-吡咯-2-乙酸1-甲基-5-(4-甲基苯甲酰)-,2-(1,2,3,6-四氢-1,3-二甲基-2,6-二氧代-7H-嘌呤-7-基)乙基酯Chemical Name: 1-Methyl-5-(4-methylbenzoyl)pyrrole-2-acetic acid 2-(theophylline-7-yl)ethyl ester; 7-[2-[2-[1-Methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetoxy]ethyl]theophylline; 1,3-Dimethyl-7-[2-[2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetoxy]ethyl]xanthine
CAS No. 104333-87-1
项目整合开发状态: Phase I
项目研究机构: Medosan (Originator)
合成路线:The reaction for preparing the esters is shown schematically by the condensation of 1-methyl-5-(4-methylbenzoyl)pyrrol-2-acetic acid and 7-(2-oxyethyl)theophylline as a general example,giving rise to the formation of the 1-methyl-5-(4-methylbenzoyl)pyrrol-2-acetate of 7-(2-oxyethyl)theophylline.
📌 参考资料/链接：
参考文献标题:Ester derivs.of 7-(omega-oxyalkyl)theophylline and their pharmaceutical activity
文献作者:Baglioni,A.(Medosan)
参考来源:EP 0177659; US 4618612
📄 详细内容
合成路线:The reaction for preparing the esters is shown schematically by the condensation of 1-methyl-5-(4-methylbenzoyl)pyrrol-2-acetic acid and 7-(2-oxyethyl)theophylline as a general example,giving rise to the formation of the 1-methyl-5-(4-methylbenzoyl)pyrrol-2-acetate of 7-(2-oxyethyl)theophylline.
参考文献标题:MED 27
文献作者:Tubaro,E.
参考来源:Drugs Fut 1993,18(7),601
产品链接: CAS No. 104333-87-1››