Bromebrate sodium, NSC-104801, Cytembena
(E)-3-(4-甲氧基苯甲酰基)-3-溴丙烯酸钠盐 (E)-3-溴-4-氧代-4-(4-甲氧基苯基)丁-2-烯酸 Chemical Name: (E)-beta-(4-Methoxybenzoyl)-beta-bromoacrylic acid sodium salt; (E)-3-Bromo-4-(4-methoxyphenyl)-4-oxo-2-butenoic acid sodium salt
CAS No. 21739-91-3, 5711-40-0 (free acid)
项目整合开发状态: Launched-1980
项目研究机构: SPOFA (Originator)
合成路线:The reaction of lambda-(4-methoxyphenyl)-alpha,beta-dibromocrotonolactone (I) with MgO in refluxing dioxane gives beta-(4-methoxy-benzoyl)-beta-bromoacrylic acid (II),which was then treated with sodium in ethanol.
📌 参考资料/链接：
参考文献标题:Cytembena
文献作者:Castar,J.; Hopkins,S.J.
参考来源:Drugs Fut 1977,2(6),374
📄 详细内容
合成路线:The reaction of lambda-(4-methoxyphenyl)-alpha,beta-dibromocrotonolactone (I) with MgO in refluxing dioxane gives beta-(4-methoxy-benzoyl)-beta-bromoacrylic acid (II),which was then treated with sodium in ethanol.
参考文献标题:Substanzen mit antineoplasticher wirksamkeit.V.Solvolyse einiger gamma-aryl-alpha,beta-dihalogen-delta(alpha,beta)-crotonlactone
文献作者:Semonsk? M.; et al.
参考来源:Coll Czech Chem Commun 1963,28377
产品链接: CAS No. 21739-91-3›› 产品链接: CAS No.5711-40-0››