Zinoconazole hydrochloride, SC-38390
(E)-1-(5-氯-2-噻吩基-2-(1H)-咪唑-1-基)乙酮(2,6-二氯苯基)腙盐酸盐 齐诺康唑 Chemical Name: 1-(5-Chloro-2-thienyl)-2-(1H-imidazol-1-yl)ethanone (E)-(2,6-dichlorophenyl)hydrazone monohydrochloride; (5-Chloro-2-thienyl)(imidazol-1-ylmethyl)ketone (E)-(2,6-dichlorophenyl)hydrazone monohydrochloride
CAS No. 80168-44-1, 84697-21-2 (free base)
项目整合开发状态: Biological Testing
项目研究机构: Pfizer (Originator)
合成路线:By reaction of 1-(5-chloro-2-thienyl)-2-(1H-imidazol-1-yl)ethanone (II) with 2,6-dichlorophenylhydrazone hydrochloride (I) in refluxing methanol.
📌 参考资料/链接：
参考文献标题:Zinoconazole hydrochloride
文献作者:Castar,J.; Prous,J.
参考来源:Drugs Fut 1985,10(7),580
📄 详细内容
合成路线:By reaction of 1-(5-chloro-2-thienyl)-2-(1H-imidazol-1-yl)ethanone (II) with 2,6-dichlorophenylhydrazone hydrochloride (I) in refluxing methanol.
参考文献标题:Synthesis of (E)-1-(5-chlorothien-2-yl)-2-(1H-imidazol-1-yl)ethanone 2,6-dichlorophenylhydrazone hydrochloride,a novel,orally active antifungal agent
文献作者:Dyer,R.L.; Ellames,G.J.; Hamill,B.J.; Manley,P.W.; Pope,A.M.
参考来源:J Med Chem 1983,26(3),442
产品链接: CAS No. 80168-44-1›› 产品链接: CAS No.84697-21-2››