SK&F-88070
Chemical Name: [6R-[6alpha,7beta(Z)]]-7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[[1-[2-(sulfoamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid disodium salt; 7beta-[syn-2-Methoxyimino-2-(2-amino-4-thiazolyl)acetamido]-3-[1-(2-sulfamidoethyl)tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acid disodium salt
CAS No. 80994-53-2 (free acid)
项目整合开发状态: Biological Testing
项目研究机构: GlaxoSmithKline (Originator)
合成路线:By reaction of 7-[syn-2-methoxyimino-2-(2-amino-4-thiazolyl)acetamido]cephalosporanic acid (I) with 1-(2-sulfamidoethyl)tetrazol-5-thiol (II) in hot water containing NaHCO3.
📌 参考资料/链接：
参考文献标题:7-[2-Alkoxyimino-2-(aminothiazole)acetamido]-3-[1-sulfaminoalkyl)tetrazolthiomethyl]cephalosporins
文献作者:Berges,D.A.; Dunn,G.L.(SmithKline Beecham Corp.)
参考来源:EP 0043713; JP 57045189; US 4308267
📄 详细内容
合成路线:By reaction of 7-[syn-2-methoxyimino-2-(2-amino-4-thiazolyl)acetamido]cephalosporanic acid (I) with 1-(2-sulfamidoethyl)tetrazol-5-thiol (II) in hot water containing NaHCO3.
参考文献标题:SKF-88070
文献作者:Castar,J.; Serradell,M.N.; Burnie,J.; Matthews,R.
参考来源:Drugs Fut 1985,10(6),476
产品链接: CAS No. 80994-53-2››