CT-32228
Chemical Name: N-(4-Bromophenyl)-6-(5-chloro-2-methylphenyl)-1,3,5-triazine-2,4-diamine
CAS No. 521064-34-6
项目整合开发状态: Preclinical
项目研究机构: Cell Therapeutics (Originator)
合成路线:The cyclization of 1-(4-bromophenyl)biguanide (I) with 5-chloro-2-methyl benzoic acid methyl ester (II) by means of NaOEt in refluxing ethanol gives the target triazine derivative.
📌 参考资料/链接：
参考文献标题:6-Phenyl-N-phenyl-(1,3,5)-triazine-2,4-diamine derivs.and related cpds.with lysophosphatidic acid acyltransferase beta (LPAAT-beta) inhibitory activity for use in the treatment of cancer
文献作者:Klein,J.P.; Gong,B.; Kumar,A.M.; Bhatt,R.; Tulinsky,J.; Hong,F.; Jenkins,S.A.(Cell Therapeutics,Inc.)
参考来源:US 2003153570; WO 0337346