INO-2628(free base), INO-2628CZ
1,4-双(环丙基甲基)哌嗪 Chemical Name: 1,4-Bis(cyclopropylmethyl)piperazine dihydrochloride; N,N-Dicyclopropylmethylpiperazine dihydrochloride
CAS No. 82909-97-5, 82909-96-4 (free base)
项目整合开发状态: Phase I
项目研究机构: Innothera (Originator)
合成路线:The reaction of cyclopropylmethyl chloride or cyclopropylmethyl bromide (Ia-b) with piperazine (II) by means of Na2CO3 in anhydrous DMF gives N,N-dicyclopropylmethylpiperazine.
📌 参考资料/链接：
参考文献标题:Cyclopropylmethyl piperazines,the process for preparing the same and their use in therapeutics
文献作者:Robba,M.F.; Aurousseau,M.E.(Laboratoire Innothera SA)
参考来源:CA 1171085; EP 81401516; FR 8021527; JP 163681; US 4474783
📄 详细内容
合成路线:The reaction of cyclopropylmethyl chloride or cyclopropylmethyl bromide (Ia-b) with piperazine (II) by means of Na2CO3 in anhydrous DMF gives N,N-dicyclopropylmethylpiperazine.
参考文献标题:INO-2628 CZ
文献作者:Leclerc,G.
参考来源:Drugs Fut 1985,10(11),907
产品链接: CAS No. 82909-97-5›› 产品链接: CAS No.82909-96-4››