PQ
Chemical Name: Acetic acid 2,6-dimethoxy-4-(9-oxo-1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-3-ylidenemethyl)phenyl ester
CAS No. 371766-68-6
项目整合开发状态: Preclinical
项目研究机构: Universidad de Murcia (Originator), Universidad de Valencia (Originator)
合成路线:Deoxyvascinone (III) is prepared from o-azidobenzoyl chloride (I) and 2-pyrrolidinone (II) following a reported procedure.Then,Claisen-Schmidt condensation between deoxyvascinone (III) and 4-acetoxy-3,5-dimethoxybenzaldehyde (IV) in boiling acetic anhydride leads to the title compound.
📌 参考资料/链接：
参考文献标题:Inhibition of leukocyte functions by the alkaloid isaindigotone from Isatis indigotica and some new synthetic derivatives
文献作者:Molina,P.; Tarraga,A.; Gonzalez-Tejero,A.; Rioja,I.; Ubeda,A.; Terencio,M.C.; Alcaraz,M.J.
参考来源:J Nat Prod 2001,64(10),1297