CB-403

(2E)-3-[2-[(2-甲基苯基)甲氧基]苯基]-2-丙烯醛Chemical Name: 3-[2-(2-Methylbenzyloxy)phenyl]-2(E)-propenal
CAS No. 302356-18-9
项目整合开发状态: Preclinical
项目研究机构: Korea Res. Inst. Biosci. Biotechnol. (Originator)
合成路线:2-Hydroxycinnamic acid (I) is converted to its methyl ester (II) by treatment with diazomethane.After reduction of the ester (II) with DIBAL,the resultant cinnamyl alcohol (III) is oxidized to aldehyde (IV) using manganese dioxide.Finally,the phenol (IV) is alkylated with the benzyl halide (V) to yield the corresponding benzyl ether.