LY-180299
(1S,4aS)-6-甲氧基-1,4a-二甲基-9-氧基-1,2,3,4,4a,9,10,10a-辛氢苯蒋-1-羧酸Chemical Name: (1S,4aS,10aR)-6-Methoxy-1,4a-dimethyl-9-oxo-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid methyl ester
CAS No. 901-36-0, 94669-34-8 (stereoisomer)
项目整合开发状态: Biological Testing
项目研究机构: Lilly (Originator)
合成路线:The methylation of podocarpic acid (I) (J Org Chem 1974,39: 1968) gives methyl O-methylpodocarpate (II),which is oxidized with CrO3 in acetic acid.
📌 参考资料/链接：
参考文献标题:Anti-viral method
文献作者:Colacino,J.M.; Hornback,W.J.; Mauldin,S.C.; Munroe,J.E.; Tang,J.C.-C.(Eli Lilly and Company)
参考来源:WO 9741849
📄 详细内容
合成路线:The methylation of podocarpic acid (I) (J Org Chem 1974,39: 1968) gives methyl O-methylpodocarpate (II),which is oxidized with CrO3 in acetic acid.
参考文献标题:Anti-viral cpds.
文献作者:Hornback,W.J.; Munroe,J.E.(Eli Lilly and Company)
参考来源:EP 0806408; JP 2000510468; WO 9741822
合成路线:The methylation of podocarpic acid (I) (J Org Chem 1974,39: 1968) gives methyl O-methylpodocarpate (II),which is oxidized with CrO3 in acetic acid.
参考文献标题:Anti-viral cpds.
文献作者:Hornback,W.J.; Mauldin,S.C.; Munroe,J.E.(Eli Lilly and Company)
参考来源:EP 0806411; JP 2000510464; WO 9742154
产品链接: CAS No. 901-36-0››