ZYC-3

Chemical Name: 2-(1-Adamantyl)-3-hydroxyestra-1,3,5(10)-trien-17-one
CAS No. 21003-01-0
项目整合开发状态: Preclinical
项目研究机构: Univ. North Texas Health Science Center (Originator), University of Florida (Originator), Washington University (Originator)
合成路线:The title compound is obtained by Friedel-Crafts alkylation of estrone (I) with 1 adamantanol (II) in the presence of boron trifluoride etherate.
📌 参考资料/链接:
参考文献标题:Modified,hydroxy-substd.aromatic structures having cytoprotective activity
文献作者:Covey,D.F.(Washington University)
参考来源:WO 0236605