KMUP-1
Chemical Name: 7-[2-[4-(2-Chlorophenyl)piperazin-1-yl]ethyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 7-[2-[4-(2-Chlorophenyl)piperazin-1-yl]ethyl]-1,3-dimethylxanthine; 7-[2-[4-(2-Chlorophenyl)piperazin-1-yl]ethyl]theophylline
CAS No. 81996-46-5
项目整合开发状态: Preclinical
项目研究机构: Kaohsiung Medical University (Originator)
合成路线:The title compound was prepared by alkylation of N-(2-chlorophenyl)piperazine (II) with 7-(2-bromoethyl)theophylline (I) in refluxing benzene.
📌 参考资料/链接：
参考文献标题:Antiphlogistic/antipyretic/analgesic agents containing theobromine or theophylline derivs.as active ingredient
文献作者:Kaneko,T.; Sugimoto,H.; Ozaki,S.; Takizawa,K.(Eisai Co.,Ltd.)
参考来源:DE 3307395; EP 0087810; US 4543254
📄 详细内容
合成路线:The title compound was prepared by alkylation of N-(2-chlorophenyl)piperazine (II) with 7-(2-bromoethyl)theophylline (I) in refluxing benzene.
参考文献标题:Theophylline and theobromine derivs.
文献作者:Nakamura,T.; Sugimoto,H.; Daiku,Y.; Igarashi,T.; Hamazo,S.(Eisai Co.,Ltd.)
参考来源:US 4426383; US 4564617
产品链接: CAS No. 81996-46-5››