MC-5723

Chemical Name: 1-Hydroxy-1-[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methylphosphonic acid
CAS No. 357966-09-7
项目整合开发状态: Preclinical
项目研究机构: Medicure (Originator)
合成路线:Addition of di-tert-butyl phosphite (II) to the pyridine aldehyde (I) afforded the pyridylphosphonate (III).The tert-butyl phosphonate esters and the cyclic ketal groups of (III) were then hydrolyzed under acidic conditions to furnish the title compound.