新产品编号:832641

Chemical Name: [2(1)-Decyl-3,3,7,8,12,13,17,18-octaethyl-3H-benzo[at]porphyrinato(2-)]zinc; (SP-4-2)-[20-Decyl-5,6,10,11,15,16,22,22-octaethyl-4,7:14,17-diimino-2,21-methano-9,12-nitrilo-12H-1-benzacyclononadecinato(2-)-kappaN1,kappaN23,kappaN24,kappaN25]zinc
CAS No. 332108-89-1
项目整合开发状态: Preclinical
项目研究机构: Roswell Park Cancer Institute (Originator)
合成路线:The reaction of octaethylporphyrin (I) with 3-(dimethylamino)acrolein (II) by means of POCl3 gives the 10-(2-formylvinyl)octaethylporphyrin (III),which is treated with decylmagnesium bromide (IV) in THF to yield the corresponding alcohol (V).The cyclization of (V) in concentrated H2SO4 affords the decylbenzochlorin (VI),which is finally treated with zinc acetate in methanol/dichloromethane to provide the target zinc complex.