新产品编号:318491
Chemical Name: N'-[1-[4(S)-(3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyloxy)-2(S),5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydronaphthacen-2-yl]-2-hydroxyethylidene]-2-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl]acetohydrazide hydrochloride
CAS No. 202407-74-7
项目整合开发状态: Preclinical
项目研究机构: Universit鋞 Freiburg (Originator)
合成路线:The title hydrazone was prepared by condensation of doxorubicin hydrochloride (I) with 4-maleimidophenylacetic acid hydrazide trifluoroacetate salt (II) in methanol.
📌 参考资料/链接：
参考文献标题:Synthesis and stability of four maleimide derivatives of the anticancer drug doxorubicin for the preparation of cemoinmunoconjugates
文献作者:Kratz,F.; Schumacher,P.; Beyer,U.; Zahn,H.; Unger,C.; Kr黦er,M.
参考来源:Chem Pharm Bull 1997,45(2),399-401