Elaidic acid-Cytarabine, P-4055
Chemical Name: 5'-O-[9(E)-Octadecenoyl]-1-beta-D-arabinofuranosylcytosine; 4-Amino-1-[5-O-[9(E)-octadecenoyl]-beta-D-arabinofuranosyl]-2(1H)-pyrimidinone
CAS No. 188181-42-2
项目整合开发状态: Preclinical
项目研究机构: Norsk Hydro (Originator)
合成路线:The title cytarabine 5'-ester was synthesized by condensation of cytarabine - HCl (I) with elaidoyl chloride (II) in DMA.
📌 参考资料/链接:
参考文献标题:Improved therapeutic agents
文献作者:Borretzen,B.; Myhren,F.; Dalen,A.; Stokke,K.T.(Norsk Hydro AS)
参考来源:WO 9705154