新产品编号:517823

Chemical Name: 3'-Azido-5'-O-[4-bromophenoxy[1-(methoxycarbonyl)ethylamino]phosphoryl]-3'-deoxythymidine
CAS No. 220693-38-9
项目整合开发状态: Biological Testing
项目研究机构: Parker Hughes Institute (Originator)
合成路线:Treatment of p-bromophenol (I) with phosphoryl chloride and triethylamine furnished p-bromophenyl phosphorodichloridate (II),which was condensed with alanine methyl ester (III) to give the intermediate phosphorochloridate (IV).Then,coupling of chloridate (IV) with azidothimidine (V) in the presence of N-methylimidazole yielded the title compound.