新产品编号:437141

Chemical Name: 2-Acetyl-4,8-dihydrobenzo[12,-b:5,4-b']dithiophene-4,8-dione
CAS No. 215371-62-3
项目整合开发状态: Biological Testing
项目研究机构: China Medical College (Originator), National Institutes of Health (Originator), University of North Carolina (Originator)
合成路线:Friedel-Crafts acetylation of the known 4-acetoxybenzodithiophene (I) with acetyl chloride and AlCl3 produced ketone (II).Subsequent chromic acid oxidation of (II) in AcOH gave quinone (III).Reduction of the methyl ketone of (III) by means of NaBH4 in MeOH afforded alcohol (IV),which was finally acetylated using acetyl chloride to furnish the title acetate ester.

合成路线:Friedel-Crafts acetylation of the known 4-acetoxybenzodithiophene (I) with acetyl chloride and AlCl3 produced ketone (II).Subsequent chromic acid oxidation of (II) in AcOH yielded the title quinone.