R-146225

Chemical Name: (-)-2-[3,5-Dichloro-4-[1-(4-chlorophenyl)-1-(2-pyrimidinylsulfanyl)methyl]phenyl]-1,2,4-triazine-3,5(2H,4H)-dione
CAS No. 219979-42-7
项目整合开发状态: Preclinical
项目研究机构: Janssen (Originator)
合成路线:The title compound was prepared by condensation of chloro derivative (I) with 2-mercaptopyrimidine (II) in the presence of DBU in THF.