BM-212

Chemical Name: 1-[1,5-Bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-ylmethyl]-4-methylpiperazine
CAS No. 146204-42-4
项目整合开发状态: Biological Testing
项目研究机构: Universit?degli Studi "La Sapienza" (Originator)
合成路线:Friedel-Crafts acylation of chlorobenzene (I) with levulinic acid chloride (II) afforded diketone (III),which was converted to pyrrole (V) by condensation with 4-chloroaniline (IV) in the presence of a catalytic amount of HBr.Mannich reaction of (V) with formaldehyde and N-methylpiperazine (VI) then provided the target aminomethyl pyrrole.