Caproctamine
Chemical Name: N,N'-Octamethylenebis[6-[N-(2-methoxybenzyl-N-methylamino]-N-methylhexanamide]
CAS No. 216174-98-0
项目整合开发状态: Biological Testing
项目研究机构: Universit?degli Studi di Bologna (Originator)
合成路线:Reductive condensation of diamine diamide (I) with 2-methoxybenzaldehyde (II) in the presence of NaBH4 provided the corresponding bis(2-methoxybenzyl) derivative (III).Then,Eschweiler-Clarke methylation using formaldehyde and formic acid provided the title compound.
📌 参考资料/链接：
参考文献标题:Acetylcholinesterase noncovalent inhibitors based on a polyamine backbone for potential use against Alzheimer's disease
文献作者:Melchiorre,C.; Andrisano,V.; Bolognesi,M.L.; Budriesi,R.; Cavalli,A.; Cavrini,V.; Rosini,M.; Turmiatti,V.; Recanatini,M.
参考来源:J Med Chem 1998,41(22),4186