新产品编号:353295

Chemical Name: 2-(3-Chlorophenyl)-4-phenyl-6,7-dihydro-5H-pyrido[3,2-d][1]benzazepin-6-one
CAS No. 205048-68-6
项目整合开发状态: Preclinical
项目研究机构: Universit鋞 Hamburg (Originator)
合成路线:Benzazepinedione (I) was condensed with propenone (II) in the presence of a catalytic amount of KOH in ethanol to furnish a diasteromeric mixture of the Michael adducts (III).This mixture was then cyclized and oxidized by means of ammonium ferric sulfate and ammonium acetate in refluxing acetic acid to provide the desired pyridobenzazepinone.