Viqualine hydrochloride, PK-5078
维喹啉 Chemical Name: 6-Methoxy-4-[3-[(3R,4R)-3-vinyl-4-piperidyl]propyl]quinoline; 4-(R)-[3-(6-Methoxy-4-quinolyl)propyl]-3(R)-vinylpiperidine; (3R-cis)-4-[3-(3-Ethenyl-4-piperidinyl)propyl]-6-methoxyquinoline
CAS No. 65843-79-0 (diHCl), 72714-74-0 (free base)
项目整合开发状态: Phase III
项目研究机构: Aventis Pharma (Originator), Pharmindustrie (Originator)
合成路线:Viqualine can be obtained by a Wolff-Kishner reduction of viquidil (I) with hydrazine in diethylene glycol followed by formation of the HCl salt with hydrochloric acid.
📌 参考资料/链接：
参考文献标题:Viqualine
文献作者:Castar,J.; Blancafort,P.; Serradell,M.N.
参考来源:Drugs Fut 1983,8(6),521
📄 详细内容
合成路线:Viqualine can be obtained by a Wolff-Kishner reduction of viquidil (I) with hydrazine in diethylene glycol followed by formation of the HCl salt with hydrochloric acid.
参考文献标题:Quinolines derivatives
文献作者:Campseix,A.; Gueremy,C.; Le Fur,G.
参考来源:DE 2727144; FR 2354771; GB 1546537; JP 52156933
合成路线:Viqualine can be obtained by a Wolff-Kishner reduction of viquidil (I) with hydrazine in diethylene glycol followed by formation of the HCl salt with hydrochloric acid.
参考文献标题:
文献作者:
参考来源:JP 8022696
合成路线:Viqualine can be obtained by a Wolff-Kishner reduction of viquidil (I) with hydrazine in diethylene glycol followed by formation of the HCl salt with hydrochloric acid.
参考文献标题:Viqualine Hydrochloride
文献作者:Serradell,M.N.; Castar,J.
参考来源:Drugs Fut 1984,9(6),434-435
产品链接: CAS No.72714-74-0››