Minaprine hydrochloride, 30038CM, Agr-1240, Alcas, Cantor
米那卜林盐酸盐 Chemical Name: 3-(2-Morpholinoethylamino)-4-methyl-6-phenylpyridazine dihydrochloride; 4-[2-[(4-Methyl-6-phenyl-3-pyridazinyl)amino]ethyl]morpholine dihydrochloride
CAS No. 25953-17-7, 25905-77-5 (free base)
项目整合开发状态: Withdrawn-1996
项目研究机构: Sanofi-Aventis (Originator), Taisho (Licensee)
合成路线:By condensation of 3-chloro-4-methyl-6-phenylpyridazine (I) with N-(2-aminoethyl)morpholine (II) by means of powdered Cu in refluxing n-butanol.
📌 参考资料/链接：
参考文献标题:Minaprine
文献作者:Castar,J.
参考来源:Drugs Fut 1977,2(12),811
📄 详细内容
合成路线:By condensation of 3-chloro-4-methyl-6-phenylpyridazine (I) with N-(2-aminoethyl)morpholine (II) by means of powdered Cu in refluxing n-butanol.
参考文献标题:Pyridazine derivatives in alleviating depressive states
文献作者:Laborit,H.
参考来源:CH 546769; DE 2229215; ES 403998; FR 2141697; GB 1345880; US 4169158
合成路线:By condensation of 3-chloro-4-methyl-6-phenylpyridazine (I) with N-(2-aminoethyl)morpholine (II) by means of powdered Cu in refluxing n-butanol.
参考文献标题:Pyridazine derivatives
文献作者:Laborit,H.
参考来源:ZA 7300671
产品链接: CAS No. 25953-17-7›› 产品链接: CAS No.25905-77-5››