ZT-1
米莫派唑Chemical Name: (5R,9R)-5-(5-Chloro-2-hydroxy-3-methoxybenzylideneamino)-11-ethylidene-7-methyl-1,2,5,6,9,10-hexahydro-5,9-methanocycloocta[b]pyridin-2-one
CAS No. 180694-97-7
项目整合开发状态: Phase II
项目研究机构: Shanghai Institute Materia Medica (Originator), Debiopharm (Licensee), H3 Pharma (Licensee)
合成路线:The title imine compound is prepared by condensation of huperzine A (I) with 5-chloro-2-hydroxy-3-methoxybenzaldehyde (II) in boiling EtOH.
📌 参考资料/链接：
参考文献标题:Huperzine A derivs.,their preparation and their use
文献作者:Zhu,D.; Tang,X.; Li,J.; Zhu,C.; Shen,J.; Wu,G.; Jiang,S.; Yamaguchi,T.; Tanaka,K.; Wakanatsu,T.; Nishimura,H.(Shanghai Institute Materia Medica; Tsumura & Co.)
参考来源:EP 0806416; JP 1998511651; US 5929084; WO 9620176