JWS-USC-75IX

Chemical Name: N-[2-[5-(Dimethylaminomethyl)-2-furylmethylsulfanyl]ethyl]-4-nitropyridazin-3-amine
CAS No. 142744-34-1
项目整合开发状态: Preclinical
项目研究机构: University of Georgia (Originator), University of South Carolina (Originator)
合成路线:Condensation of primary amine (I) with 1,1-bis(methylthio)-2-nitroethene (II) in refluxing acetonitrile afforded adduct (III).Displacement of the methylthio group of (III) by hydrazine yielded compound (IV),which was finally condensed with glyoxal (V) in the presence of Triton B to produce the target pyridazine.