SNK-882
Chemical Name: 2-(2-Oxopyrrolidin-1-yl)-N-(perhydropyrrolizin-7a-ylmethyl)acetamide hydrochloride
CAS No. 152221-12-0, 108005-79-4 (free base)
项目整合开发状态: Phase III
项目研究机构: Sanwa (Originator)
合成路线:By condensation of 7alpha-(aminomethyl)pyrrolizidine (I) with 2-(2-oxo-pyrrolidin-1-yl)acetic acid methyl ester (II) by heating at 80 C.
📌 参考资料/链接：
参考文献标题:2-Oxopyrrolidine pharmaceutical compounds,salts and the preparation thereof
文献作者:Kurono,M.; Hayashi,M.; Suzuki,T.; Miura,K.; Kumagai,Y.; Matsumoto,Y.; Miyano,S.; Sumoto,K.(Sanwa Kagaku Kenkyusho Co.,Ltd.)
参考来源:EP 0213713; JP 1987022785; US 4678801
📄 详细内容
合成路线:By condensation of 7alpha-(aminomethyl)pyrrolizidine (I) with 2-(2-oxo-pyrrolidin-1-yl)acetic acid methyl ester (II) by heating at 80 C.
参考文献标题:SNK-882
文献作者:Prous,J.; Graul,A.; Castar,J.
参考来源:Drugs Fut 1994,19(8),744
产品链接: CAS No. 152221-12-0››