NNC-22-0215
Chemical Name: (+)-7-Chloro-1-(5,6-dichloro-2,3-dihydrobenzofuran-7-yl)-8-hydroxy-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
CAS No. 172306-73-9
项目整合开发状态: Preclinical
项目研究机构: Novo Nordisk (Originator)
合成路线:By chlorination of (+)-7-chloro-1-(2,3-dihydrobenzofuran-7-yl)-8-hydroxy-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine (I) with Cl2 in glacial acetic acid.
📌 参考资料/链接：
参考文献标题:2,3,4,5-Tetrahydro-1H-3-benzazepines and pharmaceutically acceptable acid addition salts thereof
文献作者:Foged,C.; Hohlweg,R.; Nielsen,E.B.(Novo Nordisk A/S)
参考来源:EP 0628039; JP 1995504172; US 5470850; WO 9317012