Fexinidazole, Hoe-239
非昔硝唑Chemical Name: 1-Methyl-2-[4-(methylsulfanyl)phenoxymethyl]-5-nitro-1H-imidazole
CAS No. 59729-37-2
项目整合开发状态: Biological Testing
项目研究机构:
合成路线:By condensation of 4-(methylmercapto)phenol (II) with 1-mehtyl-2-chloromethyl-5-nitroimidazole (I) by means of K2CO3 in DMF.(1,2)
📌 参考资料/链接：
参考文献标题:Chemotherapeutically active nitro compounds.4,5-Nitroimidazoles.Part III
文献作者:Winkelman,E.; Raether,W.
参考来源:Arzneim-Forsch Drug Res 1978,28(5),739
📄 详细内容
合成路线:By condensation of 4-(methylmercapto)phenol (II) with 1-mehtyl-2-chloromethyl-5-nitroimidazole (I) by means of K2CO3 in DMF.(1,2)
参考文献标题:Fexinidazole
文献作者:Blancafort,P.; Serradell,M.N.; Castar,J.
参考来源:Drugs Fut 1980,5(3),125
合成路线:By condensation of 4-(methylmercapto)phenol (II) with 1-mehtyl-2-chloromethyl-5-nitroimidazole (I) by means of K2CO3 in DMF.(1,2)
参考文献标题:
文献作者:Winkelmann,E.; Raether,W.(Hoechst AG)
参考来源:DE 2531303
产品链接: CAS No. 59729-37-2››