Anipamil
阿尼帕米Chemical Name: alpha-Dodecyl-3-methoxy-alpha-[3-[N-[2-(3-methoxyphenyl)ethyl]-N-methylamino]propyl]benzeneacetonitrile; 2-[3-[N-[2-(3-Methoxyphenyl)ethyl]-N-methylamino]propyl]-2-(3-methoxyphenyl)tetradecanitrile; 1,7-Bis-(3-methoxyphenyl)-3-methyl-3-aza-7-cyanononadecane
CAS No. 83200-10-6
项目整合开发状态: Phase III
项目研究机构: Abbott (Originator)
合成路线:By condensation of 2-(3-methoxyphenyl)tetradecanenitrile (I) [prepared by alkylation of 3-methoxyphenylacetonitrile (III) with 1-bromoundecane (IV) with 1-chloro-4-methyl-6-(3-methoxyphenyl)-4-azahexane (II) (prepared by alkylation of N-methyl-[2-(3-methoxyphenyl)ethylamine (VI) with 1-bromo-3-chloropropane (V)) by means of sodium amide in refluxing toluene.
📌 参考资料/链接：
参考文献标题:omega-Cyano-1,omega-diphenyl-azaalkiane derivatives,their preparation and drugs containing them
文献作者:Ehrmann,O.; et al.(BASF AG)
参考来源:DE 3144150
📄 详细内容
合成路线:By condensation of 2-(3-methoxyphenyl)tetradecanenitrile (I) [prepared by alkylation of 3-methoxyphenylacetonitrile (III) with 1-bromoundecane (IV) with 1-chloro-4-methyl-6-(3-methoxyphenyl)-4-azahexane (II) (prepared by alkylation of N-methyl-[2-(3-methoxyphenyl)ethylamine (VI) with 1-bromo-3-chloropropane (V)) by means of sodium amide in refluxing toluene.
参考文献标题:Anipamil
文献作者:Castar,J.; Prous,J.
参考来源:Drugs Fut 1986,11(3),171
产品链接: CAS No. 83200-10-6››