合成路线:The acetylation of midecamycin (SF-837 antibiotic) (I) with acetic anhydride in hot pyridine (1,3),or with acetyl chloride and Molecular Sieve 4A-30 in dichloromethane (2,4) gives 9,2',3''-triacetylmidecamycin (II),which is partially deacetylated in hot aqueous methanol.
参考文献标题:Process for the production of a 9,3''-diacyl derivative of a macrolide antibiotic
文献作者:Nakamura,T.; Nakabayashi,S.; Fukatsu,S.; Seki,S.(Meiji Seika Kaisha,Ltd.)
参考来源:DE 2835547; FR 2400524; GB 2003145; JP 54032493; US 4188480
合成路线:The acetylation of midecamycin (SF-837 antibiotic) (I) with acetic anhydride in hot pyridine (1,3),or with acetyl chloride and Molecular Sieve 4A-30 in dichloromethane (2,4) gives 9,2',3''-triacetylmidecamycin (II),which is partially deacetylated in hot aqueous methanol.
参考文献标题:Miokamycin
文献作者:Castar,J.; Serradell,M.N.; Blancafort,P.
参考来源:Drugs Fut 1983,8(9),790
合成路线:The acetylation of midecamycin (SF-837 antibiotic) (I) with acetic anhydride in hot pyridine (1,3),or with acetyl chloride and Molecular Sieve 4A-30 in dichloromethane (2,4) gives 9,2',3''-triacetylmidecamycin (II),which is partially deacetylated in hot aqueous methanol.
参考文献标题:Modifications of a macrolide antibiotic midecamycin (SH-837).I.Synthesis and structure of 9,3''-diacetylmidecamycin
文献作者:Inouye,S.; Iwamatsu,K.; Niida,T.; Omoto,S.
参考来源:J Antibiot 1976,24(5),536-548
合成路线:The acetylation of midecamycin (SF-837 antibiotic) (I) with acetic anhydride in hot pyridine (1,3),or with acetyl chloride and Molecular Sieve 4A-30 in dichloromethane (2,4) gives 9,2',3''-triacetylmidecamycin (II),which is partially deacetylated in hot aqueous methanol.
参考文献标题:A convenient method for the preparation of the acylated macrolide antibiotic midecamycin using molecular sieves and acylchloride
文献作者:Fukatsu,S.; Seki,S.; Nakamura,T.; Niida,T.
参考来源:Chem Lett 1978,(11),1293-96
产品链接: CAS No. 55881-07-7›› 产品链接: CAS No.35457-80-8››