Aclatonium napadisilate, TM-723, Abovis
萘二磺酸乙乳胆铵Chemical Name: Bis[2-(2-acetoxypropionyloxy)-N,N,N-trimethylethanaminium] 1,5-naphthalenedisulfonate
CAS No. 55077-30-0
项目整合开发状态: Launched
项目研究机构: Toyama (Originator)
合成路线:The reaction of dimethyl naphthalene-1,5-disulfonate (I) with dimethylaminoethanol (II) gives bis (2-hydroxyethyltrimethylammonium)naphthalene-1,5-disulfonate (III),which is then condensed with 2-acetoxypropionic anhydride (IV) in refluxing acetonitrile
📌 参考资料/链接:
参考文献标题:Aclatonium Napadisilate
文献作者:Castar,J.; Prous,J.
参考来源:Drugs Fut 1982,7(4),227
📄 详细内容
合成路线:The reaction of dimethyl naphthalene-1,5-disulfonate (I) with dimethylaminoethanol (II) gives bis (2-hydroxyethyltrimethylammonium)naphthalene-1,5-disulfonate (III),which is then condensed with 2-acetoxypropionic anhydride (IV) in refluxing acetonitrile
参考文献标题:
文献作者:Miura,K.; et al.(Tomaya Chem.Co.,Ltd.)
参考来源:DE 2425983; FR 2233045; GB 1436978FR 2233045; JP 7513320; JP 7518413; JP 7721490; JP 7785118; JP 7837334; JP 8001251; US 3903137
产品链接: CAS No. 55077-30-0››