Teoprolol, D-13312(hydrochloride)
茶丙洛尔Chemical Name: 7-[3-[2-Hydroxy-3-(2-methyl-1H-indol-4-yloxy)propylamino]butyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 7-[3-[2-Hydroxy-3-(2-methyl-1H-indol-4-yloxy)propylamino]butyl]teophylline
CAS No. 65184-10-3
项目整合开发状态: Not Determined
项目研究机构:
合成路线:Teoprolol has been synthesized as follows: 2-methyl-4-hydroxyindole (I) reacts with epichlorohydrin (II) to the epoxide (III).The alkylation of theophylline alkylamine (IV) with (III) yields teoprolol.
📌 参考资料/链接：
参考文献标题:
文献作者:Offermans,H.; Klingler,K.H.; Thiemer,K.; Stroman,F.
参考来源:DE 2716210; GB 1527543; US 4144340
📄 详细内容
合成路线:Teoprolol has been synthesized as follows: 2-methyl-4-hydroxyindole (I) reacts with epichlorohydrin (II) to the epoxide (III).The alkylation of theophylline alkylamine (IV) with (III) yields teoprolol.
参考文献标题:Teoprodol
文献作者:Klinger,K.H.; Stroman,F.; Thiemer,K.; Engel,J.
参考来源:Drugs Fut 1982,7(11),825
产品链接: CAS No. 65184-10-3››