Mitozantrone hydrochloride, Mitoxantrone hydrochloride, DAD, NSC-301739, CL-232315, Onkotrone, Novantrone, Novantron

盐酸米托蒽醌 米托蒽醌 Chemical Name: 1,4-Dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]-9,10-anthracenedione dihydrochloride
CAS No. 70476-82-3, 65271-80-9 (free base)
项目整合开发状态: Launched-1984
项目研究机构: Amgen (Originator), Wyeth Pharmaceuticals (Originator), Baxter Oncology (Not Determined), OSI (Marketer), Serono (Licensee), Takeda (Licensee)
合成路线:By reaction of 5,8-dihydroxyleucoquinizarin (1,4,5,8-tetrahydroxy-9,10-anthraquinone) (I) with 2-(aminoethylamino)ethanol (II) in dioxane at 60 C.